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American Serenade, Upper Mississippi River Cruise ex St. Paul to Alton

8 Night Cruise Only


Cruise Itinerary
Date Port Arrive Depart
1 Aug 2025 St Paul, Minnesota, USA Hotel
2 Aug 2025 Red Wing, Minnesota, USA Embark
3 Aug 2025 Winona, Minnesota, USA
4 Aug 2025 Dubuque, Iowa, USA
5 Aug 2025 Davenport, Iowa, USA
6 Aug 2025 Fort Madison, Iowa, USA
7 Aug 2025 Hannibal, Missouri, USA
8 Aug 2025 St Louis, Missouri, USA
8 Aug 2025 Alton, Illinois, USA
9 Aug 2025 Alton, Illinois, USA Disembark
7 Night Cruise sailing from Red Wing to Alton onboard American Serenade. Complimentary hotel stay pre-cruise in St Paul.

Cruise Overview:

A journey along the Upper Mississippi River is an enriching experience, embodying hometown Americana and the breathtaking scenery that has inspired the country’s most legendary writers, artists, and musicians. It was here that the great American writer Mark Twain used the majestic river and its scenic bluffs as the settings in his most popular works. In his book “Life on the Mississippi,” he described traveling on this part of the river as “always through enchanting scenery, there being no other kind on the Upper Mississippi.” Visit his boyhood home in Hannibal, where the characters of Huck Finn, Tom Sawyer, and Becky Thatcher come to life.

Explore the beautiful gardens and historic homes of the region in the company of our carefully selected expert guides. From your private balcony, admire stretches of undeveloped countryside, ornamented with pelicans, soaring eagles, and blue herons. Weave among hundreds of picturesque islands and through the amazing engineering of dams and navigation locks.

Along the way, be treated to the gracious hospitality of our crew and savor an exquisite menu, featuring dishes masterfully prepared by our culinary team, with a dash of local flavor.

NOTE: Just as it was back in Mark Twain’s day, every riverboat on the Mississippi River is unique due to fluctuating river conditions that can have an impact on our itinerary. The river has a mind of its own and our sailing schedules must adapt to it. This is part of the adventure and American Cruise Lines will always work to provide a seamless travel experience.

American Cruise Lines is pleased to announce American Serenade, one of the newest ships in our revolutionary American riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Mississippi River in 2023.

Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.

American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. The new ship also features an on board fitness center and many spacious lounges where you can relax after the day’s adventures.


Ship Profile & Stats
  • Maiden voyage: 2023
  • Passenger capacity (dbl): 175
American Cruise Lines is the leader in small ship cruising! Carrying up to 180 maximum depending on the vessel, all of the small ships are able to easily navigate America's smooth, inland waterways and dock in the heart of each charming port. From Maine to Florida, the itineraries are designed to allow passengers to experience intimately each area's local culture, fascinating history and natural splendor.

Unsurpassed personal attention and intimate ambience make American Cruise Lines the leader in small ship cruising. The all-American crew is friendly, polite and eager to pamper you. Highly skilled chefs treat passengers to delectable feasts, masterfully prepared with the utmost in care and quality, highlighting the flavors of the local regions.

Refreshingly casual, flexible and unregimented - American Cruise Lines provides an intimate ambience conducive to camaraderie. Curl up with a book in the library, chat with new friends in one of the lounges, or watch the passing scenery from one of the open observation decks.

Each night, passengers relive the day's adventures over complimentary cocktails and hors d'oeuvres before dinner.

AAC Private Balcony
AAC staterooms are conveniently located on the second deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.

Veranda Suite Private Balcony
With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.

Grand Suite Private Balcony
The luxurious Grand Suite measures 650 sq. ft. and offers panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a private balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Single Private Balcony
Perfect for the solo traveler, our Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.

AAR Private Balcony
AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space. Enjoy a full-size bathroom, large picture window, and door leading out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.

AAM Private Balcony
Located on the third deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.
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*All prices are per person twin share unless stated as solo, triple or quad share.
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