American Serenade, Complete Mississippi River Cruise ex New Orleans to St. Paul

21 Night Cruise sailing from New Orleans to St Paul onboard American Serenade. Complimentary hotel stay pre-cruise in New Orleans.

Cruise Overview:

Sail 1,393 miles, through 10 states, on the most comprehensive exploration of the Mighty Mississippi available. This epic cruise showcases the culture and cuisine of the historic South, and the rolling farmlands of the Midwest as we explore the entire length of this legendary river. We embrace the relaxed pace of life on the River, following its bends and savoring its charms in much the same way as travelers and colonists would have over a century before.

Our onboard experts bring the stories of the River to life and provide context to each shore experience we provide along the way. This epic 22-day exploration of America begins in New Orleans and travels north, visiting new ports of call each day before concluding in Minneapolis.

American Cruise Lines is pleased to announce American Serenade, one of the newest ships in our revolutionary American riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Mississippi River in 2023.

Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.

American Serenade also showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms offer full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. The new ship also features an on board fitness center and many spacious lounges where you can relax after the day’s adventures.

American Cruise Lines is the leader in small ship cruising! Carrying up to 180 maximum depending on the vessel, all of the small ships are able to easily navigate America's smooth, inland waterways and dock in the heart of each charming port. From Maine to Florida, the itineraries are designed to allow passengers to experience intimately each area's local culture, fascinating history and natural splendor.

Unsurpassed personal attention and intimate ambience make American Cruise Lines the leader in small ship cruising. The all-American crew is friendly, polite and eager to pamper you. Highly skilled chefs treat passengers to delectable feasts, masterfully prepared with the utmost in care and quality, highlighting the flavors of the local regions.

Refreshingly casual, flexible and unregimented - American Cruise Lines provides an intimate ambience conducive to camaraderie. Curl up with a book in the library, chat with new friends in one of the lounges, or watch the passing scenery from one of the open observation decks.

Each night, passengers relive the day's adventures over complimentary cocktails and hors d'oeuvres before dinner.